effect of synergistic ablation and heat shock on the rat plantaris muscle.

effect of synergistic ablation and heat shock on the rat plantaris muscle. by Bruce Frier Download PDF EPUB FB2

Thirty-two female rats were randomly assigned to four groups: control (C), synergistic ablation (ABL) of the gastrocnemius and plantaris muscles to overload the soleus muscle, hindlimb suspension (HLS), or a combination of synergistic ablation and hindlimb suspension (HLS-ABL).Cited by: The synergist muscle ablation model induces muscle hypertrophy in only a few days, thereby facilitating the study of adaptive responses.2,3,7,The most studied muscles are plantar flexors in the rear paw of by:   Although the soleus muscle comprises only 6% of the ankle plantar flexor mass in the rat, a major role in stance and walking has been ascribed to it.

Cited by: 7. Plantaris muscle hypertrophy was induced by a unilateral ablation of synergistic muscles after a week. Food intake of soy protein-fed mice was higher than that of caseinate and whey-fed mice.

OR “ablation of synergists” AND “compensatory hyper - trophy” AND “experimental models” OR “skeletal muscle cross-sectional area.” The following criteria were used for the selection of papers: (1) the use of a rat model; (2) the use of synergist ablation to overload the plantaris muscle.

Skeletal muscle can undergo rapid growth in response to a sudden increase in work load. For example, the rat soleus muscle increases in weight by 40% within six days after the tendon of the.

MG muscle neurovascular grafting and synergist muscle ablation procedures. As previously described by Larkin et al. (), the tendon and nerve of the left MG muscle were severed, and the muscle was grafted orthotopically with repair of the nerve and y, animals were anesthetized with pentobarbital sodium (65 mg/kg).

Mechanical loading can increase tendon cross-sectional area (CSA), but the mechanisms by which this occurs are largely unknown. To gain a greater understanding of the cellular mechanisms of adult tendon growth in response to mechanical loading, we used a synergist ablation model whereby a tenectomy of the Achilles tendon was performed to induce growth of the synergist plantaris tendon.

Early response of heat shock proteins to functional overload of the soleus and plantaris in rats and mice Effects of gender and functional overload on plantaris muscle morphology in the dwarf (HsdOla:dw-4) Lewis rat.

Life Sciences, Vol. 65, No. 23 Synergistic ablation does not affect atrophy or altered myosin heavy chain expression in. muscle ablation. To study the effect of nerve-repair grafting on met-abolic and contractile function in skeletal muscle, we needed to find a muscle that is large enough to collect adequate samples for determining several assays of metabolic function and that has an accessible muscle with a fiber-type composition comparable to that of humans.

Synergist ablation surgery involves the surgical removal of the gastrocnemius and soleus muscles resulting in functional overload of the remaining plantaris muscle. This functional overload results in myofiber hypertrophy, as well as the activation, proliferation, and. Start studying Muscles: Action, Antagonist and Synergist.

Learn vocabulary, terms, and more with flashcards, games, and other study tools. The purpose of this study was to investigate whether the soleus muscle undergoes atrophy and alterations in myosin heavy chain (MHC) composition durin.

rat plantaris muscle. It was hypothesized that elevating Hsp content within the plantaris muscle via a single heat stress, prior to subjecting the plantaris muscle to overload by surgical removal of synergistic muscles, would ame-liorate any acute stress effects and thus lead to greater hypertrophy.

MATERIALS AND METHODS. The choice between a centrifugal radial approach and a centripetal convergent one depends on several clinical factors ().When several small targets need to be treated simultaneously (paucimultinodular disease) and/or at close time intervals (recurrent multicentric forms of disease), the simplicity and speed of conventional centrifugal ablative techniques emerge as essential benefits.

Rat PLT muscle was subjected to compensatory overload following removal of the gastrocnemius and soleus of each hindlimb. Animals were randomly assigned to control and overload groups. Overload muscles were harvested at 3 days and 1, 2, and 4 wk after synergistic ablation.

The actual ablation process is quite simple and involves the delivery of approximately cc of local anesthetic through the probe cannula, just prior to ablation, normally at 90ºC for 90 seconds.

The tip of the probe creates a sphere of heat sufficient to disrupt the myelin sheath, which is. Start studying Prime Mover, Synergists, Antagonists, Fixators. Learn vocabulary, terms, and more with flashcards, games, and other study tools.

Start studying Lower Leg Muscles - Action, Antagonist, Synergist. Learn vocabulary, terms, and more with flashcards, games, and other study tools.

Although the “heat sink” effect of tumor perfusion is a primary contributor to ablation outcome (10, 11), multiple other factors—including electrical and thermal conductivity—have been observed to influence coagulation in ex vivo tissues, suggesting further underlying differences in the sensitivity of tissues to RF energy application.

A work-induced hypertrophy model, employing the removal of the synergists involved in plantar flexion (synergistic ablation) of the rat hindlimb, is well established; previous studies have documented the biochemical and anthropomorphic changes to the rat plantaris muscle following ablation-induced overload (Noble et alLocke et al Effects of heat shock transcription factor 1 (HSF1) gene on the regrowth of atrophied mouse soleus muscles were studied.

Protein synthesis in rat plantaris muscle undergoing surgically induced. Synergists (down) and Antagonists (Across) Glenohumerol Joint (Ball and Socket): Flexion: Extension: Deltoid (Anterior Fibers). The changes induced by overload model in plantaris muscle of rats resulted in a significant increase muscle mass (up to an increase of 10% to 30% in the cross section of the muscle fibers seconds.

The time course of angiogenesis during hypertrophy of the rat plantaris muscle was studied by using a unilateral, synergistic ablation model. Animals (n = 6/group) were euthanized 2, 5, 7, 15, 21, and 30 days ns from both the hypertrophied and contralateral muscles were simultaneously stained for capillaries and muscle fiber type.

Heat shock protein 20 was the least responsive, increasing only in 7 day FO rat plantaris compared with control rats. Overall, the results demonstrate that levels of both large and small HSPs increase with FO, suggesting a contributory role during the compensatory hypertrophy response.

Heat shock proteins (Hsps) are molecular chaperones that aid in protein synthesis and trafficking and have been shown to protect cells/tissues from various protein damaging stressors. To determine the extent to which a single heat stress and the concurrent accumulation of Hsps influences the early events of skeletal muscle hypertrophy, Sprague-Dawley rats were heat stressed (42°C, 15.

The purpose of this study was to determine if heat shock could provide protection to skeletal muscle as has been shown in cardiac muscle. A minute heat shock at 42 degrees C resulted in an. Synergistic Co-activation Increases the Extent of Mechanical Interaction between Rat Ankle Plantar-Flexors The Harvard community has made this article openly available.

Please share how this access benefits you. Your story matters Citation Tijs, Chris, Jaap. In the rat hindlimb, muscle fibre types differ widely between soleus (86% type I) and the muscles making up the white portion of the gastrocnemius (95% type IIB), with varying proportions in other sections of the gastrocnemius–plantaris–soleus (GPS) complex (Delp & Duan, ).

Surgical ablation is an animal model involving surgical removal of a muscle, thereby overloading its synergistic muscles and Heat shock protein for plantaris muscle in young and aging animals for Age-related alterations in expression of apoptosis regulatory proteins and heat shock proteins in rat skeletal muscle.

Biochimica et. The diversity of muscle fibers allows them to perform specialized functional tasks. Thus the type I fibers with high oxidative capacity and capillary density are more suitable for endurance exercise while type IIb fibers with low oxidative capacity and capillary density are suitable for short term IIa are the intermediate fiber types that allow high power generation at a considerable.These results indicate that effects of LG+PL MTU length changes on F SO were enhanced by synergistic muscle activation.

ANOVA indicated no effect of LG+PL length on the HRT of F SO (Figure (Figure3), 3), both during SO excitation (average across LG+PL lengths: ± ms, p = ) and during SO&LG excitation (average across LG+PL.